Opportunity Information: Apply for RFA AI 18 054
The U.S.-Brazil Collaborative Biomedical Research Program (R01 Clinical Trial Optional) is a National Institutes of Health (NIH) funding opportunity designed to strengthen and expand biomedical research partnerships between investigators in the United States and Brazil. The core aim is to support high-quality, jointly planned projects that take advantage of complementary expertise, populations, research infrastructure, and public health priorities in both countries. The mechanism used is the NIH R01, meaning applicants are generally expected to propose a mature, hypothesis-driven research project with a clear plan, strong preliminary rationale, and well-defined milestones. Clinical trials are allowed but not required, so applications can range from basic and translational studies to clinical and implementation-oriented research, as long as the work fits the program’s scientific scope and meets NIH requirements for human subjects research when applicable.
The scientific focus is centered on biomedical areas where U.S.-Brazil collaboration can have strong impact, particularly in allergy, immunology, and infectious diseases. A major emphasis is on HIV/AIDS and related complications, including HIV co-morbidities and intersections with cancer. The announcement also highlights priority topics involving prevention and treatment across the life course, especially mother-to-child transmission of HIV and other congenital infections, as well as early infant diagnosis and treatment. Another explicitly supported area is HIV/AIDS as it relates to mental health and neurological outcomes, including neurological disorders and stroke. In practical terms, this scope encourages projects that address mechanisms of disease, improved diagnostics, therapeutic strategies, vaccine or prevention approaches, and the clinical and public health consequences of infection, including complex co-morbidity patterns that may differ by region or population.
From an applicant eligibility standpoint, the FOA is broadly open to many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. It also includes federally recognized Native American tribal governments, tribal organizations that are not federally recognized, public housing authorities/Indian housing authorities, and other categories NIH often calls out for inclusion and capacity-building, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). Faith-based or community-based organizations and eligible federal agencies are also listed as able to apply, as are U.S. territories or possessions and certain regional organizations. This wide eligibility is meant to allow participation by a diverse range of research-performing institutions and community partners, which can be especially important for clinical, behavioral, and implementation research.
At the same time, the FOA places clear boundaries on non-U.S. applicant organizations. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the primary applicant, and non-domestic components of U.S. organizations are also not eligible to apply as applicant organizations. However, foreign components, as defined under the NIH Grants Policy Statement, are allowed. In practice, that means a U.S. institution typically serves as the applicant/awardee and can include a foreign component to conduct part of the project in Brazil when justified scientifically and operationally. This structure is consistent with the program’s purpose: supporting true collaboration while keeping award administration under an eligible U.S. applicant institution.
Administratively, this opportunity is categorized as a discretionary grant program administered by NIH. It is identified by Funding Opportunity Number RFA-AI-18-054 and is associated with multiple CFDA numbers (93.113, 93.242, 93.853, 93.855, 93.865), reflecting NIH’s multi-institute and multi-topic funding authorities that can support the stated health areas. The original closing date listed for this specific announcement was March 8, 2019, and the record shows a creation date of December 4, 2018. No award ceiling or expected number of awards is specified in the provided source data, which is not unusual for NIH RFAs depending on how the initiative is structured and budgeted. Overall, the opportunity is best understood as an NIH R01 pathway specifically targeted to projects that are genuinely collaborative between U.S. and Brazilian partners and that address high-priority biomedical questions in immunology and infectious diseases, with particular attention to HIV/AIDS, maternal and child health, and neurological and mental health impacts.Apply for RFA AI 18 054
- The National Institutes of Health in the environment, health, income security and social services sector is offering a public funding opportunity titled "U.S.-Brazil Collaborative Biomedical Research Program (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.853, 93.855, 93.865.
- This funding opportunity was created on 2018-12-04.
- Applicants must submit their applications by 2019-03-08. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R01 Clinical Trial Not Allowed) Apply for PAR 19 292 Funding Number: PAR 19 292 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Development of Novel and Robust Systems for Mechanistic Studies of Gene-Environment Interplay in Dental, Oral, Craniofacial, and Other Diseases and Conditions (R21 Clinical Trial Not Allowed) Apply for PAR 19 293 Funding Number: PAR 19 293 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03 Clinical Trial Not Allowed) Apply for PAR 20 065 Funding Number: PAR 20 065 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $75,000 |
| Small Research Grants for Analyses of Down Syndrome-related Research Data for the INCLUDE Project (R03 Clinical Trial Not Allowed) Apply for RFA OD 20 006 Funding Number: RFA OD 20 006 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 20 005 Funding Number: RFA OD 20 005 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism Spectrum Disorders (R01 Clinical Trial Optional) Apply for PA 21 201 Funding Number: PA 21 201 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism Spectrum Disorders (R21 Clinical Trial Optional) Apply for PA 21 200 Funding Number: PA 21 200 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Research on Autism Spectrum Disorders (R03 Clinical Trial Optional) Apply for PA 21 199 Funding Number: PA 21 199 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Autism Centers of Excellence: Centers (P50 Clinical Trial Optional) Apply for RFA HD 22 008 Funding Number: RFA HD 22 008 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Autism Centers of Excellence: Networks (R01 Clinical Trial Optional) Apply for RFA HD 22 007 Funding Number: RFA HD 22 007 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) Apply for PAR 21 319 Funding Number: PAR 21 319 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional) Apply for PAR 21 311 Funding Number: PAR 21 311 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) Apply for PAR 22 098 Funding Number: PAR 22 098 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional) Apply for PAR 22 097 Funding Number: PAR 22 097 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed) Apply for PAR 23 171 Funding Number: PAR 23 171 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional) Apply for PAR 23 319 Funding Number: PAR 23 319 Agency: National Institutes of Health Category: Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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