Opportunity Information: Apply for PAR 23 112
This NIH grant opportunity (PAR-23-112) is an R01 program focused on funding intervention research that directly addresses structural racism and discrimination (SRD) as a way to improve minority health outcomes and/or reduce health disparities. The core idea is not simply to document inequities, but to test practical, evidence-based interventions that can change policies, systems, institutional practices, community conditions, or other structural drivers that produce unequal health outcomes across racial and ethnic groups and other underserved populations. The notice is labeled "Clinical Trial Optional," meaning applicants may propose either clinical trial or non-clinical trial intervention studies, as long as the work is intervention-focused and aligned with the goal of reducing disparities linked to SRD.
The administering agency is the National Institutes of Health (NIH), and the funding mechanism is a discretionary grant under the R01 activity code. The opportunity sits within a broad health and social-services policy space (reflected in the multiple CFDA/Assistance Listing numbers provided), which signals that NIH is open to a range of health topics and disciplines as long as the project centers on structural racism/discrimination as a fundamental cause and tests an intervention that could plausibly improve health equity. In practice, competitive projects typically make a clear connection between (1) a specific structural mechanism (for example, discriminatory housing or lending practices, inequitable school funding, biased clinical algorithms, unequal access to environmental protections, or exclusionary immigration-related barriers), (2) a target population experiencing minority health burdens or documented disparities, and (3) a measurable set of health or health-related outcomes that the intervention is designed to improve.
A wide range of applicants are eligible. Standard eligible applicants include state, county, and local governments; special districts; independent school districts; public and private institutions of higher education; federally recognized tribal governments; public housing authorities/Indian housing authorities; tribal organizations (including those other than federally recognized tribal governments); nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other entities. The opportunity also explicitly highlights additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This emphasis strongly suggests NIH is encouraging applications that are rooted in communities most affected by structural inequities and that involve institutions with strong community ties and cultural competence.
At the same time, there are strict limitations on foreign involvement. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply. Non-domestic components of U.S. organizations are not eligible, and foreign components (as NIH defines them in the NIH Grants Policy Statement) are not allowed. In other words, the applicant organization must be U.S.-based, and the proposed work must be carried out without a foreign component.
The listing provides an award ceiling of $500,000, indicating the funding expects projects to be scoped at a level consistent with an R01 but with a defined cap in this source summary. The posting does not specify the number of expected awards in the provided text. The original closing date shown is January 7, 2026, and the opportunity was created January 30, 2023. Overall, this program is best suited for applicants who can design rigorous intervention research that targets structural-level causes of inequity, demonstrates meaningful engagement with affected communities and stakeholders, and produces results that could be scaled, sustained, or translated into policy and practice to improve minority health and reduce health disparities.Apply for PAR 23 112
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.242, 93.279, 93.286, 93.307, 93.313, 93.361, 93.847, 93.859, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2023-01-30.
- Applicants must submit their applications by 2026-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 23 112) also looked into and applied for these:
| Funding Opportunity |
|---|
| Emergency Award: Novel Insights through Cross-Site Analyses of Existing RADx-UP Data (R21 Clinical Trial Not Allowed) Apply for RFA OD 23 050 Funding Number: RFA OD 23 050 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $275,000 |
| Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional) Apply for PAR 23 166 Funding Number: PAR 23 166 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Collaborative Partnership to Advance Global Health Research (U01 Clinical Trial Not Allowed) Apply for PAR 23 203 Funding Number: PAR 23 203 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $2,360,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 23 260 Funding Number: PA 23 260 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 23 272 Funding Number: PA 23 272 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 23 262 Funding Number: PA 23 262 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 23 261 Funding Number: PA 23 261 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Apply for PA 23 271 Funding Number: PA 23 271 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 24 141 Funding Number: PA 24 141 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) Apply for PA 24 185 Funding Number: PA 24 185 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) Apply for PA 24 184 Funding Number: PA 24 184 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required) Apply for PA 24 190 Funding Number: PA 24 190 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed) Apply for PA 24 191 Funding Number: PA 24 191 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required) Apply for PA 24 175 Funding Number: PA 24 175 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) Apply for PA 24 176 Funding Number: PA 24 176 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) Apply for PA 24 182 Funding Number: PA 24 182 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) Apply for PA 24 193 Funding Number: PA 24 193 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) Apply for PA 24 194 Funding Number: PA 24 194 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed) Apply for PAR 24 131 Funding Number: PAR 24 131 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) Apply for PAR 24 152 Funding Number: PAR 24 152 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $375,000 |
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